Journal of Neural Transmission

, Volume 35, Issue 2, pp 175–178

Antagonism by nialamide of the ethanol-induced locomotor stimulation in mice

  • S. Ahlenius
  • R. Brown
  • J. Engel
  • T. H. Svensson
  • B. Waldeck
Short Communication

DOI: 10.1007/BF01250743

Cite this article as:
Ahlenius, S., Brown, R., Engel, J. et al. J. Neural Transmission (1974) 35: 175. doi:10.1007/BF01250743

Summary

Administration of ethanol (2 g/kg, 20% w/v i.p.) to mice produced a significant increase in their locomotor activity. Pretreatment with the monoamine oxidase inhibitor nialamide, whichper se had no marked effect on the locomotor activity, prevented the ethanol-induced locomotor stimulation. The possibility that this effect of nialamide is mediated by a feed-back mechanism is discussed.

Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • S. Ahlenius
    • 1
  • R. Brown
    • 1
  • J. Engel
    • 1
  • T. H. Svensson
    • 1
  • B. Waldeck
    • 1
  1. 1.Department of PharmacologyUniversity of GöteborgSweden

Personalised recommendations