Journal of Neural Transmission / General Section JNT

, Volume 93, Issue 1, pp 71–74

Dopamine D2 receptor alteration in patients with periodic movements in sleep (nocturnal myoclonus)

Authors

  • J. Staedt
    • Department of PsychiatryGeorg August University
  • G. Stoppe
    • Department of PsychiatryGeorg August University
  • A. Kögler
    • Department of Nuclear MedicineGeorg August University
  • D. Munz
    • Department of Nuclear MedicineGeorg August University
  • H. Riemann
    • Department of PsychiatryGeorg August University
  • D. Emrich
    • Department of Nuclear MedicineGeorg August University
  • E. Rüther
    • Department of PsychiatryGeorg August University
Short Communication

DOI: 10.1007/BF01244940

Cite this article as:
Staedt, J., Stoppe, G., Kögler, A. et al. J. Neural Transmission (1993) 93: 71. doi:10.1007/BF01244940

Summary

Periodic movements in sleep (PMS) can cause severe sleep disturbances. We investigated the central dopamine D2 receptor density in patients with PMS with123I-IBZM and single photon emission tomography (SPET). In PMS there was a lower123I-IBZMbinding in the basal ganglia compared tothe control group. The results indicate a loss of central D2 receptors in PMS.

Keywords

Dopamine receptorsocturnal myoclonusPMSSPET

Copyright information

© Springer-Verlag 1993