Journal of Cancer Research and Clinical Oncology

, Volume 121, Issue 12, pp 701–709

Cytokines and bone marrow transplantation

  • Fujimaro Takaku
Review Paper

DOI: 10.1007/BF01213315

Cite this article as:
Takaku, F. J Cancer Res Clin Oncol (1995) 121: 701. doi:10.1007/BF01213315


This article summarizes the various current uses of cytokines, and bone marrow and peripheral blood stem cell transplantation for cancer treatment. Interferons, interleukin-2 and hematopoietic growth factors are extensively used for the treatment of hematopoietic as well as nonhematopoietic malignancies, either as the main therapeutic agents or as an adjuvant. Research on gene therapy using cytokines is in progress. Stem cell transplantation is also discussed in the context of gene therapy of cancer. Gene therapy is expected to become a future modality in cancer treatment.

Key words

Interferon Interleukin-2 Hematopoietic growth factors Bone marrow transplantation Peripheral blood stem cell transplantation 

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • Fujimaro Takaku
    • 1
  1. 1.International Medical Center of JapanTokyoJapan