Original Article

International Journal of Biometeorology

, Volume 39, Issue 2, pp 59-63

First online:

Solar activity cycle and the incidence of foetal chromosome abnormalities detected at prenatal diagnosis

  • Gabrielle J. HalpernAffiliated withDepartment of Medical Genetics, Beilinson Medical Center
  • , Eliahu G. StoupelAffiliated withDivision of Cardiology, Beilinson Medical CenterThe Sackler Faculty of Medicine, Tel Aviv University
  • , Gad BarkaiAffiliated withInstitute of Medical Genetics, Sheba Medical CenterThe Sackler Faculty of Medicine, Tel Aviv University
  • , Rina ChakiAffiliated withInstitute of Medical Genetics, Sheba Medical Center
  • , Cyril LegumAffiliated withGenetic Institute, Elias Sourasky Medical Center, Ichilov HospitalThe Sackler Faculty of Medicine, Tel Aviv University
  • , Moshe D. FejginAffiliated withMedical Genetics Unit, Meir HospitalThe Sackler Faculty of Medicine, Tel Aviv University
  • , Mordechai ShohatAffiliated withDepartment of Medical Genetics, Beilinson Medical CenterThe Sackler Faculty of Medicine, Tel Aviv University

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Abstract

We studied 2001 foetuses during the period of minimal solar activity of solar cycle 21 and 2265 foetuses during the period of maximal solar activity of solar cycle 22, in all women aged 37 years and over who underwent free prenatal diagnosis in four hospitals in the greater Tel Aviv area. There were no significant differences in the total incidence of chromosomal abnormalities or of trisomy between the two periods (2.15% and 1.8% versus 2.34% and 2.12%, respectively). However, the trend of excessive incidence of chromosomal abnormalities in the period of maximal solar activity suggests that a prospective study in a large population would be required to rule out any possible effect of extreme solar activity.

Key words

Solar activity Chromosomal abnormality Trisomy