Microchimica Acta

, Volume 94, Issue 1, pp 139–141

FT-IR analysis of single human normal and leukemic lymphocytes

  • Enzo Benedetti
  • Piergiorgio Vergamini
  • Giuliano Spremolla
Special Sampling (IRRAS, Microscopy, High Pressure, TGA-FTIR)

DOI: 10.1007/BF01205856

Cite this article as:
Benedetti, E., Vergamini, P. & Spremolla, G. Mikrochim Acta (1988) 94: 139. doi:10.1007/BF01205856

Abstract

The infrared spectra of single human normal and leukemic lymphocytes have been obtained by means of the microscope-FT-IR system. Substantial differences between the two kinds of cells have been observed at level of the O-P-O vibrations of the DNA and of the proteic components. This determination opens up the possibility in determining the early stages of leukemia, in following the course of patients under therapy, and in evaluation of the residual neoplastic disease.

Key words

FT-IR microspectrometryleukemialymphocytes

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • Enzo Benedetti
    • 1
  • Piergiorgio Vergamini
    • 1
  • Giuliano Spremolla
    • 2
  1. 1.Dipartimento di Chimica e Chimica IndustrialeUniversity of PisaPisaItaly
  2. 2.1a Clinica MedicaUniversity of PisaPisaItaly