, Volume 23, Issue 1, pp 79-90

Differentiating pervasive developmental disorder not otherwise specified from autism and language disorders

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Features useful in distinguishing choldren with pervasive developmental disorder (PDD) from those with autism or language disorder were developed from a retrospective chart review using groups of children with PDD-NOS and MA-and sex-matched autistic and language-disordered groups. Charts were reviewed using a list of 80 items compiled from various sources. Items that had adequate interrater reliability and significantly discriminated the PDD-NOS cases from the language-disordered or autistic cases were then evaluated using a second set of cases and signal detection methods. Fewer items significantly discriminated cases with autism from those with PDD-NOS as compared to cases with language disorder. Clinical implications are discussed.

From the Yale Child Study Center (Mayes, Volkmar, and Hooks) and the Veterans Administration Medical Center, West Haven, Connecticut (Cicchetti). Marla Hooks is currently affiliated with the University of Washington. This study was supported by grant M846961 from the National Institute of Mental Health, by grant HD-03008 from the National Institute of Child Health and Human Development, by NIMH grant MH-30929 to the Mental Health Clinical Research Center, and grant MRIS-1416 to the Veterans Administration. The authors thank Helena Kraemer for her provision of the QROC program.