Archives of Environmental Contamination and Toxicology

, Volume 15, Issue 4, pp 333–341

Polychlorobiphenyl congeners,p,p′-DDE, and sperm function in humans


  • Brian Bush
    • New York State Department of HealthWadsworth Center for Laboratories and Research
  • Alan H. Bennett
    • Albany Medical CollegeUnion University
  • John T. Snow

DOI: 10.1007/BF01066399

Cite this article as:
Bush, B., Bennett, A.H. & Snow, J.T. Arch. Environ. Contam. Toxicol. (1986) 15: 333. doi:10.1007/BF01066399


170 seminal samples from fertile men, men with idiopathic oligospermia or azoospermia and men status post vasectomy were analyzed for 74 polychlorobiphenyl (PCB) congeners,p,p′-DDE, mirex, and hexachlorobenzene using the technique of glass capillary gas chromatography with electron capture detection. Low concentrations of 32 PCB congeners were measured (mean total PCB residue of 5.8 ng/g wet weight). The application of multiple linear regression analysis to the data is described and the result is critically evaluated. There is a correlation between sperm motility and count. There are indications that the concentrations of three PCB congeners (2,4,5,2′4′5′- and 2,4,5,2′3′4′-hexachlorobiphenyl and 2,4,5,3′4′-pentachlorobiphenyl) are inversely correlated with sperm motility index in samples with a sperm count less than 20 million cells/ml. The implications of the discerned associations are discussed.

Copyright information

© Springer-Verlag New York Inc. 1986