Behavior Genetics

, Volume 5, Issue 3, pp 217–231

Open-field behavior in mice: A diallel analysis of selected lines

  • R. A. Halcomb
  • J. P. Hegmann
  • J. C. DeFries
Article

DOI: 10.1007/BF01066174

Cite this article as:
Halcomb, R.A., Hegmann, J.P. & DeFries, J.C. Behav Genet (1975) 5: 217. doi:10.1007/BF01066174

Abstract

The open-field behavior of 719 mice resulting from a diallel cross among the six lines of the DeFries selection experiment was assessed. Results of several analyses employing different models and procedures were highly consistent and indicated that genes responsible for differences in open-field activity and defecation among these lines have predominantly additive effects. Estimates of heritability obtained from these analyses were considerably higher than previous estimates based on familial resemblance or the realized response to selection; thus estimation of heritability from diallel analyses is clearly unwarranted when selected lines are employed and the character of interest has been either directly or indirectly subjected to artificial selection.

Key Words

open-field behaviormicediallel analysisselected lines

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • R. A. Halcomb
    • 1
  • J. P. Hegmann
    • 2
  • J. C. DeFries
    • 1
  1. 1.Institute for Behavioral GeneticsUniversity of ColoradoBoulder
  2. 2.Department of ZoologyUniversity of IowaIowa City