Behavior Genetics

, Volume 19, Issue 1, pp 151–161

Genetic and environmental variation in the birth weight of twins

  • R. Vlietinck
  • R. Derom
  • M. C. Neale
  • H. Maes
  • H. van Loon
  • C. Derom
  • M. Thiery
Article

DOI: 10.1007/BF01065890

Cite this article as:
Vlietinck, R., Derom, R., Neale, M.C. et al. Behav Genet (1989) 19: 151. doi:10.1007/BF01065890

Abstract

Two novel approaches to the analysis of twin data are illustrated with data from birth weight in twins. First, two possible covariates of birth weight are fitted to the data simultaneously, allowing for linear effects of these variables, and their correlation. Second, information on chorionicity is used to estimate the effects of chorion type on birth weight. The data were collected from a large sample of twins born in East Flanders, Belgium. Variation and covariation in twins were considered as a function of sex, chorionicity, maternal age, gestational age, and genotype. No evidence for sex differences in causes of variation was found. As expected, the largest source of variation in birth weight was associated with gestational age. Other common environmental influences were nonsignificant. Heritability was significant, constituting approximately 40% of variation not associated with maternal and gestational age. A small but significant effect of chorionicity was found, such that dichorionic twins show a greater similarity than monochorionic.

Key Words

twins LISREL birth weight 

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • R. Vlietinck
    • 1
  • R. Derom
    • 2
  • M. C. Neale
    • 3
  • H. Maes
    • 4
  • H. van Loon
    • 1
  • C. Derom
    • 1
  • M. Thiery
    • 2
  1. 1.Campus Gasthuisberg Onderwijs & NavorsingCentrum voor Menselijke ErfelijkheidLeuvenBelgium
  2. 2.Verloskundige KliniekUniversitair ZiekenhuisGentBelgium
  3. 3.Department of Human GeneticsMedical College of VirginiaRichmond
  4. 4.Instituut voor Lichamelijke OpleidingHeverleeBelgium

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