Psychiatric Quarterly

, Volume 64, Issue 4, pp 345–358

Genetic and biologic risk factors for suicide in depressive disorders

  • Alec Roy

DOI: 10.1007/BF01064927

Cite this article as:
Roy, A. Psych Quart (1993) 64: 345. doi:10.1007/BF01064927


Over the last few years data have accumulated suggesting that there may be genetic and biologic risk factors for suicide. This paper reviews studies from clinical populations, twins, the Amish, as well as data from the Iowa-500 and Danish-American adoption studies which suggest that there may be a genetic factor predisposing to suicide. The paper also reviews neurochemical data from cerebrospinal fluid, urine and postmortem studies which suggest that diminished central serotonin and dopamine may be implicated in suicidal behavior.

Copyright information

© Human Sciences Press, Inc 1993

Authors and Affiliations

  • Alec Roy
    • 1
  1. 1.Englewood