Journal of Pharmacokinetics and Biopharmaceutics

, Volume 11, Issue 6, pp 641–657

Computation of the explicit solution to the Michaelis-Menten equation

  • Stuart L. Beal
Article

DOI: 10.1007/BF01059062

Cite this article as:
Beal, S.L. Journal of Pharmacokinetics and Biopharmaceutics (1983) 11: 641. doi:10.1007/BF01059062

Abstract

An explicit solution to the Michaelis-Menten differential equation with bolus and zero-order input is presented. This solution involves certain simple functions whose values are not readily available. Efficient algorithms for computing values of these functions to any desired degree of accuracy and FORTRAN codes for implementing them are also given.

Key words

Michaelis-Menten equation, explicit solutionnumerical computation

Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Stuart L. Beal
    • 1
  1. 1.Department of Laboratory Medicine and Division of Clinical Pharmacology, Departments of Pharmacy and MedicineUniversity of CaliforniaSan Francisco