European journal of applied microbiology and biotechnology

, Volume 2, Issue 2, pp 91–94

Preliminary studies on streptomutin A

Authors

  • J. R. Lemke
    • Department of Nutrition and Food ScienceMassachusetts Institute of Technology
  • A. L. Demain
    • Department of Nutrition and Food ScienceMassachusetts Institute of Technology
Industrial Microbiology

DOI: 10.1007/BF00942351

Cite this article as:
Lemke, J.R. & Demain, A.L. European J. Appl Microbiol. (1976) 2: 91. doi:10.1007/BF00942351

Summary

Supplementation of the culture medium with 2-deoxystreptidine allowsStreptomyces griseus MIT-5, an idiotrophic mutant, to produce an antibiotic which we have called streptomutin A. Degradation studies on the antibiotic showed that the aminocyclitol moiety is different from streptidine. Streptomutin A also is distinct from streptomycin in having a much different ratio of biological to chemical activity.

Copyright information

© Springer-Verlag 1976