Case Reports

Surgery Today

, Volume 27, Issue 4, pp 345-348

First online:

Cronkhite-Canada syndrome associated with carcinoma of the sigmoid colon: Report of a case

  • Naoki NakatsuboAffiliated withDepartment of Surgery, Himi City Hospital
  • , Rinichiro WakasaAffiliated withDepartment of Surgery, Himi City Hospital
  • , Katsumi KiyosakiAffiliated withDepartment of Surgery, Himi City Hospital
  • , Kazuhiro MatsuiAffiliated withDepartment of Pathology, Toyama Medical and Pharmaceutical University
  • , Fumio KonishiAffiliated withDepartment of Surgery, Jichi Medical School

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Cronkhite-Canada syndrome is generally accepted as being a benign disorder. We herein present a 66-year-old-male patient with Cronkhite-Canada syndrome who had a carcinoma of the sigmoid colon along with multiple colonic polyps, which included juvenile-type polyps, adenomas, and hyperplastic polyps. In the world literature, there have been 34 cases of Cronkhite-Canada syndrome associated with colorectal carcinoma among the 280 reported cases of this syndrome. This report thus adds to the growing evidence that Cronkhite-Canada syndrome may be a premalignant condition for colorectal carcinoma. A periodic examination of the colon is therefore advised in order to detect any development of colorectal carcinoma at an early stage.

Key Words

Cronkhite-Canada syndrome colonic cancer