Influence of prolonged physical exercise on the erythropoietin concentration in blood
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- Schwandt, H.J., Heyduck, B., Gunga, H.C. et al. Europ. J. Appl. Physiol. (1991) 63: 463. doi:10.1007/BF00868079
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Erythropoietin (EPO) and red blood cells were studied in 15 well-trained men before and several times after a marathon run. Changes in red blood cells reflected changes of plasma volume. Immediately after the run, red blood cells were increased due to haemoconcentration, whereas 31 h later the values were decreased due to haemodilution. The EPO concentration was increased 3 h, and more impressive 31 h, after the run. This long-lasting increase in EPO concentration after the marathon run would seem to be responsible for the increased red blood cell mass in long distance runners.