Journal of Fluorescence

, Volume 1, Issue 4, pp 215–223

Analysis of the solvent effect on the photophysics properties of 6-propionyl-2-(dimethylamino)naphthalene (PRODAN)

  • Javier Catalan
  • Pilar Perez
  • Jose Laynez
  • F. Garcia Blanco
Article

DOI: 10.1007/BF00865246

Cite this article as:
Catalan, J., Perez, P., Laynez, J. et al. J Fluoresc (1991) 1: 215. doi:10.1007/BF00865246

Abstract

The absorption and emission spectroscopic properties of 6-propionyl-2-(dimethylamino)naphthalene (PRODAN) have been studied in a large number of protogenic, nonprotogenic, and amphiprotic solvents. The data obtained can be explained by the inclussion of a new term in the Lippert equation which takes into account the acidity of the solvent. This finding indicates that some precaution should be taken when using PRODAN as an indicator of the polarity of protein cavities if the environments involved include acid sites.

Key Words

Probes PRODAN acidity polarity 

Copyright information

© Plenum Publishing Corporation 1991

Authors and Affiliations

  • Javier Catalan
    • 1
  • Pilar Perez
    • 1
  • Jose Laynez
    • 2
  • F. Garcia Blanco
    • 3
  1. 1.Departamento de Quimica Fisica AplicadaUniversidad Autonoma de MadridMadridSpain
  2. 2.Instituto de Quimica Fisica Rocasolano CSICMadridSpain
  3. 3.Departamento de Quimica Fisica Farmaceutica, Facultad de FarmaciaUniversidad Complutense de MadridMadridSpain

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