Pediatric Nephrology

, Volume 2, Issue 2, pp 205–209

Growth from birth to adulthood in a patient with the neonatal form of bartter syndrome

  • W. Proesmans
  • G. Massa
  • M. Vanderschueren-Lodeweyckx
Original Article

DOI: 10.1007/BF00862592

Cite this article as:
Proesmans, W., Massa, G. & Vanderschueren-Lodeweyckx, M. Pediatr Nephrol (1988) 2: 205. doi:10.1007/BF00862592

Abstract

Growth from birth to the age of 19 years was studied in a patient with the neonatal form of Bartter syndrome. The initial modes of therapy (extra fluid, potassium supplements and triamterene) resulted in satisfactory but not optimal growth. Treatment with spironolactone together with potassium led to impressive catch-up growth. When the patient reached the age of 9 years, indomethacin therapy was started, which resulted in a second growth acceleration and was also accompanied by a significant reduction of both polyuria and hypercalciuria. Puberty developed normally, menarche occurred at 12 years 4 months and a normal adult height of 162 cm was reached at the age of 14 years. Treatment with prostaglandin synthetase inhibitors seems to be the best therapy for children with the neonatal form of Bartter syndrome.

Key words

Bartter syndromePolyhydramniosHypercalciuriaSpironolactoneIndomethacinGrowth retardationCatch-up growth

Copyright information

© IPNA 1988

Authors and Affiliations

  • W. Proesmans
    • 1
  • G. Massa
    • 1
  • M. Vanderschueren-Lodeweyckx
    • 1
  1. 1.Department of PaediatricsUniversity Hospital GasthuisbergLeuvenBelgium