Original Article

Pediatric Nephrology

, Volume 2, Issue 4, pp 415-418

Haemolytic uraemic syndrome and pseudomembranous colitis

  • N. RooneyAffiliated withDepartment of Pathology, Bristol Royal Infirmary
  • , S. VariendAffiliated withDepartment of Pathology, Children's Hospital
  • , L. S. TaitzAffiliated withDepartment of Paediatrics, Children's Hospital

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Two cases of haemolytic uraemic syndrome (HUS) associated with pseudomembranous colitis (PMC) are described. The toxin ofClostridium difficile was detected post mortem in the stool of one patient and the other patient showed a good therapeutic response to oral vancomycin, an antibiotic with established efficacy in the management of PMC. When associated with HUS, PMC is probably an independent specific disease that, in common with many other infections, may activate HUS.

Key words

Haemolytic uraemic syndrome Pseudomembranous colitis