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Natural electrical RF oscillation from cells

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Abstract

Electrical oscillatory rf phenomena are present during the division of cells. These were examined by studying the attraction of cells for polarizable powders. They are understood to occur by a process termed microdielectrophoresis (μ-DEP), the motion induced by a nonuniform electric field acting on a polarizable body. The suggestion that an electrical oscillatory aspect may also be involved in the “contact” or density inhibition of cell division and the mechanisms that may cause invasiveness of oncogenic cells are theoretically explored (i.e., changes in either the power level or the frequency of the oscillatory phenomena associated with cell division, or in the degree of electrical insulation of the cell from electrical damping by nearby cells). A number of experiments to test this hypothesis are suggested.

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References

  • Ackerson, E. (1962).Biophysical Sciences Prentice-Hall, Englewood Cliffs, New Jersey, p. 208.

    Google Scholar 

  • Ahuja, M. R., and Anders, F. (1977). Cancer as a problem of gene regulation, inRecent Advances in Cancer Research, Vol. I, Gallo, R. C., ed., CRC Press, pp. 103–117.

  • Ambercrombie, M., and Ambrose, E. J. (1958).Exp. Cell Res. 15 332.

    Google Scholar 

  • Belousov, B. (1958).Sb. Ref. Radiat. Med. (Collections of Abstracts on Radiation, Medicine Medgiz, Moscow, p. 145.

    Google Scholar 

  • Berridge, M. J., and Rapp, P. E. (1979).J. Exp. Biol. 81 217.

    Google Scholar 

  • Bray, W. C. (1921).J. Am. Chem. Soc. 43 1262.

    Google Scholar 

  • Busch, H. (1977). Some aspects of the molecular biology of cancer, inRecent Advances in Cancer Research, Vol. I, Gallo, R. C., ed., CRC Press, p. 2.

  • Cleary, S. F. (1979).Crit. Rev. Environ. Control 7 121.

    Google Scholar 

  • Degn, H. (1972).J. Chem. Educ. 49 302.

    Google Scholar 

  • Digby, P. (1965).Proc. Roy. Soc. B 161 504.

    Google Scholar 

  • Dvorak, H. F.,et al. (1979a)J. Natl. Cancer Inst., p. 1459.

  • Dvorak, H. F.,et al. (1979b)J. Immunol. 122 166.

    Google Scholar 

  • Fermi, E., Pasta, J. R., and Ulam, S. M. (1965). Studies of nonlinear problems,Collected Works of Enrico Fermi, Vol. II, University of Chicago Press, Chicago, p. 978.

    Google Scholar 

  • Fricke, H., and Morse, S. (1925).J. Cancer Res. 10 340.

    Google Scholar 

  • Fröhlich, H. (1973).Coop. Phenom. 1 101.

    Google Scholar 

  • Fröhlich, H. (1968).Int. J. Quantum Chem. 2 641.

    Google Scholar 

  • Gallo, R. C., Foreword inRecent Advances in Cancer Research, Vol. I, Gallo, R. C. CRC Press.

  • Hirniak, Z. (1910).Z. Phys. Chem., 675.

  • Hunter-Szybalska, M. E., Szybalski, W., and De Lemater, E. D. (1956).J. Bacteriol. 71 17.

    Google Scholar 

  • Jaffe, L. F., and Nuccitelli, R. (1977).Ann Rev. Biophys. Bioeng. 6 445.

    Google Scholar 

  • Jaffe, L. F., and Nuccitelli, R. (1974).J. Cell Biol. 63 614.

    Google Scholar 

  • Landman, O., and Halle, S. (1963).J. Mol. Biol. 7 721.

    Google Scholar 

  • Laki, K., and Ladik, J. (1976).Int. J. Quantum Chem., Quantum Biol. Symp. No. 3, 55–57.

  • Lotka, A. J. (1920).J. Am. Chem. Soc. 42 1595.

    Google Scholar 

  • Lotka, A. J. (1910).J. Phys. Chem. 14 271.

    Google Scholar 

  • McLaughlin, S. (1975). inMolecular Mechanisms of Anesthesia Fink, B. R., ed., Raven Press, New York, p. 193.

    Google Scholar 

  • Moser, J. (1979).Am. Sci. 67 689.

    Google Scholar 

  • Noyas, R. M., and Field, R. J. 1974.Ann. Rev. Phys. Chem. 25 95.

    Google Scholar 

  • Nuccitelli, R. (1977).J. Cell Biol. 75, 23a.

  • Nuccitelli, R., and Jaffe, L. F. (1975).J. Cell Biol. 64 636.

    Google Scholar 

  • Nuccitelli, R., and Jaffe, L. F. (1974).Proc. Nat'l. Acad. Sci. USA 71 4855.

    Google Scholar 

  • Pilla, A. A. (1974).Ann. N.Y. Acad. Sci. 238 149.

    Google Scholar 

  • Pohl, H. A. (1980a). Microdielectrophoresis of dividing cells,U.S.-Australian Conference on Bioelectrochemistry, September 1979 Keyzer, H. and Gutmann, F., eds., Plenum Press, New York, pp. 273–295.

    Google Scholar 

  • Pohl, H. A. (1980b). Oscillating fields about growing cells,Int. J. Quantum Chem. 7 411.

    Google Scholar 

  • Pohl, H. A. (1980c).Chem-Eng. Commun. 4 237.

    Google Scholar 

  • Pohl, H. A. (1980). Do cells in the reproductive state exhibit a Fermi-Pasta-Ulam-Fröhlich resonance and emit electromagnetic radiation?,J. Biol. Phys. 8 45–75.

    Google Scholar 

  • Pohl, H. A. (1978).Dielectrophoresis Cambridge University Press, London and New York.

    Google Scholar 

  • Pohl, H. A. and Sauer, J. R. (1978).J. Biol. Phys. 6 118.

    Google Scholar 

  • Prigogine, I. (1978).Nobel Lecture in Chemistry, 1977, Nouvelles Culturelles de Belgique, Edition spéciale, Fev.

  • Prigogine, I. (1961).Introduction to the Thermodynamics of Irreversible Processes Wiley-Interscience, New York.

    Google Scholar 

  • Prigogine, I., and Balescu, R. (1955).Bull. Cl. Sci. Acad. R. Belg. 41 917.

    Google Scholar 

  • Prigogine, I., and Balescu, R. (1956).Bull. Cl. Sci. Acad. R. Belg. 42 256.

    Google Scholar 

  • Rabai, G., Bazza, G., and Meck, M. (1979).Magyar Kem Foly. 85 378.

    Google Scholar 

  • Rapp, P. E. (1979).J. Exp. Biol. 81 281.

    Google Scholar 

  • Rodan, G. A., Bowrret, L. A., and Norton, L. A. (1978).Science 199 688.

    Google Scholar 

  • Ryter, A., and Landman, O. E. (1964).J. Bacteriol. 88 457.

    Google Scholar 

  • Schmidt, S., and Ortoleva, P. (1979).J. Chem. Phys. 71 1010.

    Google Scholar 

  • Schrödinger, E. (1945).What Is Life? Cambridge University Press, London and New York.

    Google Scholar 

  • Schwann, H. P. (1956).Adv. Biol. Med. Phys. 4 147.

    Google Scholar 

  • Scott, A. C., Chu, F. Y. U., and McLaughlin, D. W. (1973).Proc. IEEE 61 1443.

    Google Scholar 

  • Stern, S., Margolin, L., Weiss, B., Lu, S.-T., and Michaelson, S. M. (1979).Science 206 1198.

    Google Scholar 

  • Szent-Györgyi, A. (1978).The Living State and Cancer Marcel Dekker, New York.

    Google Scholar 

  • Szent-Györgyi, A. (1941).Nature 148 157.

    Google Scholar 

  • Szybalski, W., and Hunter-Szybalska, M. E. (1955).Bacteriol. Proc., p. 36.

  • Treherne, J. E., Foster, W. A. and Schofield, P. K. (1979).Cellular oscillators, J. Exp. Biol. 81.

  • Webb, S. J., Lee, R., and Stoneham, M. E. (1977).Int. J. Quantum Chem., Quantum Biol. Symp. 4 277.

    Google Scholar 

  • Weisenseel, M. H., Nuccitelli, R., and Jaffe, L. F. (1975).J. Cell. Biol. 66 556.

    Google Scholar 

  • Winfree, A. T. (1974).Sci. Am. 230 82.

    Google Scholar 

  • Zeuthen, E. (1958).Adv. Biol. Med. Phys. 6 37.

    Google Scholar 

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Pohl, H.A. Natural electrical RF oscillation from cells. J Bioenerg Biomembr 13, 149–169 (1981). https://doi.org/10.1007/BF00763837

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