Molecular mechanisms of calcium-induced membrane fusion
- Cite this article as:
- Papahadjopoulos, D., Nir, S. & Düzgünes, N. J Bioenerg Biomembr (1990) 22: 157. doi:10.1007/BF00762944
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We have reviewed studies on calcium-induced fusion of lipid bilayer membranes and the role of synexin and other calcium-binding proteins (annexins) in membrane fusion. We have also discussed the roles of other cations, lipid phase transitions, long chain fatty acids and other fusogenic molecules. Finally, we have presented a simple molecular model for the mechanism of lipid membrane fusion, consistent with the experimental evidence and incorporating various elements proposed previously.