Adams RD, Kubik CS (1944) Subacute degeneration of the brain in pernicious anemia.N Engl J Med
Amur SG, Shanker G, Cochran JM, Ved HS, Pieringer RA (1986) Correlation between inhibition of myelin basic protein (arginine) methyltransferase by sinefungin and lack of compact myelin formation in cultures of cerebral cells from embryonic mice.J Neurosci Res
Auletta A, Gery A, Parmar A, Davis J, Mishra L, Mead J (1974) The effect of folate and folate analogues upon dihydrofolate reductase and DNA synthesis in kidneys of normal mice.Life Sci
Beckman DR, Hoganson G, Berlow S, Gilbert EF (1987) Pathological findings in 5,10-methylenetetrahydrofolate deficiency.Birth Defects
Billings F (1902) The changes in the spinal cord and medulla in pernicious anemia.Boston Med Surg J
147: 225–233, 257–263.
Blackley R (1969)The Biochemistry of Folic Acid and Related Pteridines. Amsterdam: North-Holland.
Cantoni GL (1975) Biological methylation: selected aspects.Annu Rev Biochem
Carmel R, Watkins D, Goodman SL, Rosenblatt DS (1988) Hereditary defect of cobalamin metabolism (Cbl G mutation) presenting as a neurological disorder in adulthood.N Engl J Med
Clayton PT, Smith I, Harding B, Hyland K, Leonard JV, Leeming RJ (1986) Subacute combined degeneration of the cord, dementia and Parkinsonism due to an inborn error of folate metabolism.J Neurol Neurosurg Psychiatr
Crang AJ, Jacobson W (1980) The methylation in vitro of myelin basic protein by arginine methylase from mouse spinal cord.Biochem Soc Trans
Dayan AD, Ramsey RB (1974) An inborn error of vitamin B12 metabolism associated with cellular deficiency of coenzyme forms of the vitamin. Pathological and neurochemical findings in one case.J Neurol Sci
Deacon R, Purkiss P, Green R, Perry J, Chanarin I (1986) Vitamin B12 neuropathy is not due to failure to methylate myelin basic protein.J Neurol Sci
Frenkel EP (1971) Studies on the mechanism of the neural lesion of pernicious anemia.J Clin Invest
Ghosh SK, Syed SK, Jung S, Paik WK, Kim S (1990) Substrate specificity for myelin basic protein-specific protein methylase I.Biochim Biophys Acta
Hoffman DR, Marion DW, Cornatzer WE, Duerre JA (1980)S-adenosylmethionine andS-adenosylhomocysteine metabolism in isolated rat liver. Effects ofl-methionine,l-homocysteine and adenosine.J Biol Chem
Hyland K, Smith I, Bottiglieri T et al (1988) Demyelination and decreasedS-adenosylmethionine in 5,10-methylenetetrahydrofolate reductase deficiency.Neurology
Israëls MCG, Wilkinson JF (1949) Risk of neurological complications in pernicious anaemia treated with folic acid.Br Med J
Layzer RB, Fishman RA, Schaffer JA (1978) Neuropathy following abuse of nitrous oxide.Neurology
Lee C-C, Surtees R, Duchen L (1992) Distal motor axonopathy and central nervous system vacuolation caused by cycloleucine, an inhibitor of methionine adenosyltransferase.Brain
Lever EG, Elwes RDC, Williams A, Reynolds EH (1986) Subacute combined degeneration of the cord due to folate deficiency: response to methyl-folate treatment.J Neurol Neurosurg Psychiatr
Levitt M, Nixon P, Pincus J, Bertino J (1971) Transport characteristics of folate in cerebrospinal fluid; a study utilising doubly labelled 5-methyltetrahydrofolate and 5-formyltetrahydrofolate.J Clin Invest
Metz J (1992) Cobalamin deficiency and the pathogenesis of nervous system disease.Annu Rev Nutr
Lichtheim (1887) Zur kenntnis der perniciösen Anämie.Verhandl d Cong f Innere Med
Pallis CA, Lewis PD (1974)The Neurology of Gastrointestinal Disease. London: Saunders, 30.
Ramsey RB, Fischer VW (1978) Effect of 1-aminocyclopentane-1-carboxylic acid (cycloleucine) on developing rat central nervous system phospholipids.J Neurochem
Rosenberg LE, Fenton WA (1989) Disorders of propionate and methylmalonate metabolism. In Scriver CR, Beaudet AL, Sly WS, Valle D, eds.The Metabolic Basis of Inherited Disease, 6th edn. New York: McGraw-Hill, 821–844.
Russell JSR, Batten FE, Collier J (1900) Subacute combined degeneration of the spinal cord.Brain
Schatz RA, Wilens TE, Sellinger OZ (1981) Decreased transmethylation of biogenic amines after in vivo elevation of brainS-adenosyl-l-homocysteine.J Neurochem
Scott JM, Dinn J, Wilson P, Weir DG (1981) Pathogenesis of subacute combined degeneration: a result of methyl group deficiency.Lancet
Small DH, Carnegie PR (1982) In vivo methylation of an arginine in chicken myelin basic protein.J Neurochem
Small DH, Carnegie PR, Anderson RMcD (1981) Cycloleucine-induced vacuolation of myelin is associated with inhibition of protein methylation.Neurosci Lett
Smith I, Hyland K, Kendall B, Leeming R (1985) Clinical role of pteridine therapy in tetrahydrobiopterin deficiency.J Inher Metab Dis
8 (Suppl 1): 39–45.
Surtees R (1992)S-Adenosylmethionine deficiency and demyelination. A study of the metabolites of the methyl-transfer pathway in cerebrospinal fluid. PhD thesis, University of London.
Surtees R, Hyland K (1990a) Cerebrospinal fluid concentrations ofS-adenosylmethione, methionine and 5-methyltetrahydrofolate in a reference population: cerebrospinal fluidS-adenosylmethionine declines with age in humans.Biochem Med Metab Biol
Surtees R, Hyland K (1990b)l-3,4-Dihydroxyphenylalanine (levodopa) lowers central nervous systemS-adenosylmethionine concentrations in humans.J Neurol Neurosurg Psychiatr
Surtees R, Leonard J, Austin S (1991) Association of demyelination with deficiency of cerebrospinal fluidS-adenosylmethionine in inborn errors of methyl-transfer pathway.Lancet
Tabor CW, Tabor H (1976) 1,4-Diaminobutane (putrescine), spermidine and spermine.Annu Rev Biochem
Ungley C (1949) Subacute combined degeneration of the cord. I. Response to liver extracts. II. Trials with vitamin B12.Brain
van der Westhuyzen J, Fernandes-Costa F, Metz J (1982) Cobalamin inactivation by nitrous oxide produces severe neurological impairment in fruit bats: protection by methionine and aggravation by folates.Life Sci
van der Westhuyzen J, Metz J (1983) TissueS-adenosyl-methionine levels in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced neuropathy.Br J Nutr
Vieira-Makings E, Metz J, van der Westhuyzen J, Bottiglieri T, Chanarin I (1990) Cobalamin neuropathy. IsS-adenosylhomocysteine toxicity a factor?Biochem J
Vivaqua RJ, Myerson RM, Prescott DJ, Rabinowitz JL (1966) Abnormal propionic-methyl malonic-succinic acid metabolism in vitamin B12 deficiency and its possible relationship to the neurologic syndrome of pernicious anaemia.Am J Med Sci
Weir DG, Keating S, Molloy A et al (1988) Methylation deficiency causes vitamin B12-associated neuropathy in the pig.J Neurochem
Weir DG, Molloy AM, Keating JN et al (1992) Correlation of the ratio ofS-adenosyl-l-methionine toS-adenosyl-l-homocysteine in the brain and cerebrospinal fluid of the pig: implications for the determination of this methylation ratio in human brain.Clin Sci
Woltman HW (1918) Brain changes associated with pernicious anaemia.Arch Int Med
Zappia V, Salvatore F, Porcelli M, Cacciapuoti G (1979) Novel aspects in the biochemistry of adenosylmethionine and related sulphur compounds. In Zappia V, Usdin E, Salvatore F, eds.Biochemical and Pharmacological Roles of Adenosylmethionine and the Central Nervous System. Oxford: Pergamon Press, 1–16.