Acta Neuropathologica

, Volume 59, Issue 3, pp 237–239

Carbonic anhydrase-III immunohistochemical localization in human skeletal muscle

Authors

  • K. Shima
    • Section of Neurology, Dept. of NeurosurgeryHokkaido University School of Medicine
    • First Dept. of BiochemistryHokkaido University School of Medicine
  • K. Tashiro
    • Section of Neurology, Dept. of NeurosurgeryHokkaido University School of Medicine
  • N. Hibi
    • First Dept. of BiochemistryHokkaido University School of Medicine
  • Y. Tsukada
    • First Dept. of BiochemistryHokkaido University School of Medicine
  • H. Hirai
    • First Dept. of BiochemistryHokkaido University School of Medicine
Short Original Communications

DOI: 10.1007/BF00703210

Cite this article as:
Shima, K., Tashiro, K., Hibi, N. et al. Acta Neuropathol (1983) 59: 237. doi:10.1007/BF00703210

Summary

Using the indirect immunoperoxidase method, we studied the localization of carbonic anhydrase-III (CA-III) in frozen sections of biopsies of human skeletal muscle which had no definite pathology. CA-III was found to be localized in Type-I muscle fibers when compared with serial sections stained with myosin ATPase and other reactions. Our finding was in accordance with the biochemical data so far reported. It was thought that CA-III could be used as a marker for abnormal Type-I muscle fibers in several neuromuscular diseases.

Key words

Carbonic anhydraseSkeletal muscleImmunoperoxidase method

Copyright information

© Springer-Verlag 1983