Journal of Cancer Research and Clinical Oncology

, Volume 106, Supplement 1, pp 21–24

Morphological grades of regression in osteosarcoma after polychemotherapy — Study COSS 80

  • M. Salzer-Kuntschik
  • G. Delling
  • G. Beron
  • R. Sigmund
Symposium of the Cooperative Osteosarcoma Study Group — COSS 80 A Combined Diagnostic and Therapeutic Approach to Osteosarcoma Treatment May 7, 1982 in Viena

DOI: 10.1007/BF00625047

Cite this article as:
Salzer-Kuntschik, M., Delling, G., Beron, G. et al. J Cancer Res Clin Oncol (1983) 106: 21. doi:10.1007/BF00625047

Summary

The histologic grade of regression of 50 osteosarcomas after polychemotherapy — according to the protocol study, COSS 80 — was classified on a six-stage regression scale; 56% of all patients responded well to chemotherapy regression grades I, II, and III and no significant difference between BCD- and CPL-treated patients could be found. Tumors under 10 cm in length responded better to chemotherapy than those of greater length and there was a good correlation between the clinical estimation of tumor regression and progression and the histologic grade of regression.

Key words

OsteosarcomaChemotherapyHistologic grades of regression

Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • M. Salzer-Kuntschik
    • 1
  • G. Delling
    • 2
  • G. Beron
    • 3
  • R. Sigmund
    • 4
  1. 1.The Vienna Bone Tumor Registry at the Pathologic Institute of the University of ViennaViennaAustria
  2. 2.The Pathologic Institute of the University of HamburgHamburgFederal Republic of Germany
  3. 3.The Department of Blood Coagulation Research and Oncology at the Pediatric Clinic of the University of HamburgHamburgFederal Republic of Germany
  4. 4.The Orthopedic Clinic of the University of ViennaViennaAustria