Experimental Brain Research

, Volume 79, Issue 2, pp 313–318

Frequency dependent corticofugal excitation of principal cells in the cat's dorsal lateral geniculate nucleus

  • S. Lindström
  • A. Wróbel

DOI: 10.1007/BF00608240

Cite this article as:
Lindström, S. & Wróbel, A. Exp Brain Res (1990) 79: 313. doi:10.1007/BF00608240


Excitatory postsynaptic potentials (EPSPs) were evoked in principal cells of the cat's dorsal lateral geniculate nucleus by electrical stimulation of cortico-geniculate fibres. The EPSPs had a pronounced frequency sensitivity. They were barely detectable at stimulation frequencies below 3 Hz but increased dramatically in size at higher frequencies. At 30–50 Hz their amplitude typically exceeded that of EPSPs from optic tract fibres. A prominent EPSP potentiation was also obtained with pair pulse stimulation. The findings are discussed in relation to the hypothesis that the cortico-geniculate system serves as a variable gain regulator for the visual input to the cortex.

Key words

Dorsal lateral geniculate nucleusPrincipal cellsCortico-geniculate systemFrequency enhancementCat

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • S. Lindström
    • 1
  • A. Wróbel
    • 1
  1. 1.Department of PhysiologyUniversity of GöteborgGöteborgSweden
  2. 2.Department of NeurophysiologyNencki Institute of Experimental BiologyWarsawPoland