Neuroradiology

, Volume 32, Issue 1, pp 74–76

Mitochondrial encephalomyopathy (MELAS) with mental disorder

CT, MRI and SPECT findings
  • T. Suzuki
  • J. Koizumi
  • H. Shiraishi
  • N. Ishikawa
  • K. Ofuku
  • M. Sasaki
  • T. Hori
  • N. Ohkoshi
  • I. Anno
Case Reports

DOI: 10.1007/BF00593949

Cite this article as:
Suzuki, T., Koizumi, J., Shiraishi, H. et al. Neuroradiology (1990) 32: 74. doi:10.1007/BF00593949

Summary

A case of mitochondrial encephalomyopathy (MELAS) with mental disorder is reported. The SPECT study using123I-iodoamphetamine (IMP) and MRI study revealed abnormality in the left parieto-occipital areas without abnormality in the brain CT or brain scintigram. These findings suggest a localized dysfunction of the brain capillary endothelium in association with the cerebral involvement of mitochondrial encephalomyopathy.

Key words

Mitochondrial encephalomyopathyCTMRISPECT

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • T. Suzuki
    • 1
  • J. Koizumi
    • 1
  • H. Shiraishi
    • 1
  • N. Ishikawa
    • 3
  • K. Ofuku
    • 1
  • M. Sasaki
    • 1
  • T. Hori
    • 1
  • N. Ohkoshi
    • 2
  • I. Anno
    • 3
  1. 1.Department of Psychiatry Institute of Clinical MedicineThe University of TsukubaJapan
  2. 2.Department of Neurology Institute of Clinical MedicineThe University of TsukubaJapan
  3. 3.Department of Radiology, Institute of Clinical MedicineThe University of TsukubaJapan