Human Genetics

, Volume 75, Issue 2, pp 136–139

Localization of the gene for a syndrome of X-linked skeletal dysplasia and mental retardation to Xq27-qter

  • S. R. Dlouhy
  • J. C. Christian
  • J. L. Haines
  • P. M. Conneally
  • M. E. Hodes
Original Investigations

DOI: 10.1007/BF00591074

Cite this article as:
Dlouhy, S.R., Christian, J.C., Haines, J.L. et al. Hum Genet (1987) 75: 136. doi:10.1007/BF00591074

Summary

An Indiana family segregating a syndrome of X-linked mental retardation and skeletal anomalies was tested for linkage of the mutant gene to X-chromosome molecular markers. Lod scores of 3.27 and 3.06 (Θ-0) for the molecular probes St14-1 (DXS52) and Dx13 (DXS15), respectively, indicate that the disease gene is located in the terminal portion of Xq.

Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • S. R. Dlouhy
    • 1
  • J. C. Christian
    • 1
  • J. L. Haines
    • 1
  • P. M. Conneally
    • 1
  • M. E. Hodes
    • 1
  1. 1.Department of Medical GeneticsIndiana University School of MedicineIndianapolisUSA

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