Control by insulin of sodium potassium and water excretion by the isolated dog kidney
- Cite this article as:
- Nizet, A., Lefebvre, P. & Crabbé, J. Pflugers Arch. (1971) 323: 11. doi:10.1007/BF00586561
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Insulin has been shown to decrease sodium, potassium and water excretion by direct action on the kidney. Reduction of sodium excretion is due to enhanced tubular reabsorption as a probable consequence of stimulated active sodium transport. The renal effect of insulin is demonstrated with plasma hormone concentration observable in pathophysiological conditions; it offers therefore a possible explanation for some clinical findings such as the changes in sodium, potassium and water excretion occurring in man after fasting and subsequent glucose feeding.