Pflügers Archiv

, Volume 323, Issue 1, pp 11–20

Control by insulin of sodium potassium and water excretion by the isolated dog kidney

Authors

  • A. Nizet
    • Institut de MédecineUniversity of Liège
  • P. Lefebvre
    • Institut de MédecineUniversity of Liège
  • J. Crabbé
    • Institut de MédecineUniversity of Liège
    • Departement de Physiologie et de MédecineUniversité de Louvain
Article

DOI: 10.1007/BF00586561

Cite this article as:
Nizet, A., Lefebvre, P. & Crabbé, J. Pflugers Arch. (1971) 323: 11. doi:10.1007/BF00586561

Summary

Insulin has been shown to decrease sodium, potassium and water excretion by direct action on the kidney. Reduction of sodium excretion is due to enhanced tubular reabsorption as a probable consequence of stimulated active sodium transport. The renal effect of insulin is demonstrated with plasma hormone concentration observable in pathophysiological conditions; it offers therefore a possible explanation for some clinical findings such as the changes in sodium, potassium and water excretion occurring in man after fasting and subsequent glucose feeding.

Key-Words

InsulinSodium ExcretionPotassium ExcretionWater ExcretionIsolated Kidney

Schlüsselwörter

InsulinNatriumexkretionKaliumexkretionWasser-exkretionIsolierte Niere
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Copyright information

© Springer-Verlag 1971