, Volume 256, Issue 3, pp 261-263

Measurement of dermal thickness with the harpenden skinfold caliper

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A simple method of determining skin thickness using the Harpenden Skinfold Caliper is described. Using this technique the atrophy caused by the topical application of Fluocinolone acetonide in normal volunteers has been detected. As a comparison the skin thickness was also measured in the same individuals by an established x-ray technique. Not only was a similar degree of atrophy observed but also a high degree of correlation (r = 0.82,n = 32,P < 0.001) was found between the values obtained with both techniques.


Es wird eine einfache Methode beschrieben, um die Hautdicke mittels Erfassung der Hautfaltenmessung (Harpenden Skinfold Caliper) zu erfassen. Mittels dieser Technik wurde die Hautatrophie nach lokaler Anwendung von Fluocinolonacetonid erfaßt. Der Vergleich dieser physikalischen Meßmethode mit der Röntgentechnik zeigt einen hohen Grad der Korrelation beider Techniken.

The authors are in receipt of grants from the Wellcome Trust and from Organon Laboratories Ltd.