, Volume 111, Issue 4, pp 303-316

Location on the chromosome ofSalmonella typhimurium of genes governing pyrimidine metabolism

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Summary

Genes encoding the enzymes cytidine deaminase (cdd), uridine monophosphate pyrophosphorylase (upp), cytidine triphosphate synthetase (pyrG), and uridine phosphorylase (udp) were located on theSalmonella typhimurium chromosome at 68, 77, 90 and 122 min, respectively. Strains carrying mutations inpyrG must also carry mutations incdd in order for cytidine to be sufficiently stable metabolically to supply the cell's requirement for CTP1.

Communicated by W. Maas