Archives of oto-rhino-laryngology

, Volume 246, Issue 5, pp 269–270

Gentamicin and other ototoxic antibiotics for the transtympanic treatment of Menière's disease

  • G. Lange

DOI: 10.1007/BF00463571

Cite this article as:
Lange, G. Arch Otorhinolaryngol (1989) 246: 269. doi:10.1007/BF00463571


Severe unilateral cases of Menière's disease can be successfully treated with ototoxic antibiotics. Among them gentamicin sulfate gives the safest results. With the aid of a small syringe this antibiotic is introduced into the external auditory canal 5 times/ day. From there it reaches the middle ear through a ventilating tube by using a Politzer bag. Gentamicin then penetrates the round and oval windows, where it influences inner ear function. Of 92 patients treated during the past 20 years, more than 90% have had no further attacks after therapy.

Key words

Menière's disease Ototoxic antibiotics Gentamicin 

Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • G. Lange
    • 1
  1. 1.Städtische HNO-KlinikWuppertal 2Federal Republic of Germany

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