, Volume 3, Issue 2, pp 124-128

Comparison between histological, histochemical and clinical findings from musculature of pubococcygeal repair (PCR) in urinary incontinence

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Samples from both pubococcygeal muscles (PCM) of 10 pubococcygeal repairs (PCRs) were compared with each other as well as with pre- and intraoperative inspection and palpation and early postoperative findings. Muscle bundles on the left were microscopically better differentiated than on the right. Partial degeneration was recordable from all right PCMs. Slow- and fast-twitch fibers were differentiated by means of Con A-lectin. Results of this lectin-binding study were widely congruent with the outcome of fluorescence-PAS reaction. Preoperative pelvic-floor assessment and tissue findings were in good (6), partial (3) or no (1) agreement. Intraoperative muscle status was less reliable or even contradictory. PCR gave good early results even with poor muscle quality (5 cases), but PCMs were bilaterally bad in only 2 cases (1 cured, 1 not cured). Good early results even with poor muscle quality support the preliminary conclusion that connective tissue reactions are primarily responsible for PCR effectiveness.