Quality of Life Research

, Volume 2, Issue 3, pp 221–226

Interpretation of quality of life changes

  • E. Lydick
  • R. S. Epstein

DOI: 10.1007/BF00435226

Cite this article as:
Lydick, E. & Epstein, R.S. Qual Life Res (1993) 2: 221. doi:10.1007/BF00435226


The clinical significance of quality of life changes has little to do with the QOL as a measure, but is rather a reflection on the novelty of the measures and researcher's inexperience in their use. This article discusses possible ways of evaluating quality of life measures in terms of patient-clinician interactions and how the clinician can assess the importance of these changes of QOL in terms of treatment and management of disease.

Key words

Clinical significanceepidemiological studiesoutcomes researchquality of life

Copyright information

© Rapid Communications of Oxford Ltd 1993

Authors and Affiliations

  • E. Lydick
    • 1
  • R. S. Epstein
    • 1
  1. 1.Merck Research LaboratoriesPennsylvaniaUSA