Psychopharmacology

, Volume 76, Issue 3, pp 269–272

Intra-patient variability in the measurement of tardive dyskinesia

  • Mary Ann Richardson
  • Thomas J. Craig
  • Marc H. Branchey
Original Investigations

DOI: 10.1007/BF00432559

Cite this article as:
Richardson, M.A., Craig, T.J. & Branchey, M.H. Psychopharmacology (1982) 76: 269. doi:10.1007/BF00432559

Abstract

Intra-patient variability in the movements of tardive dyskinesia was examined through the analyses of 8-min frequency counts collected over a period of 11 weeks for six chronic schizophrenic patients. Weekly observation segments of 8 min, 4 min, 2 min, 1 min and 30 s showed considerable variation both across weeks and within sessions. Variations were of sufficient magnitude to contribute to the possibility of false negative tardive dyskinesia assessments and false positive treatment outcome designations. Measurement procedures taking this variability into account are urged for the study of tardive dyskinesia. Additionally, independently obtained rating scale scores showed no association to the collected frequency count data, suggesting fundamental differences between these two assessment procedures.

Key words

Tardive dyskinesiaVariabilityLecithin

Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • Mary Ann Richardson
    • 1
  • Thomas J. Craig
    • 1
  • Marc H. Branchey
    • 2
  1. 1.Clinical Systems Research and Development, Information Sciences DivisionRockland Research InstituteOrangeburgUSA
  2. 2.Alcoholism Research and Treatment CenterVA HospitalBronxUSA