, Volume 181, Issue 3, pp 409-410

Petite-negative mutants of Saccharomyces cerevisiae

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A series of yeast mutants has been isolated with the inability to grow on fermentable carbon sources whilst growing normally on ethanol media. One of the mutants, namely MC16/206 lacks pyruvate decarboxylase activity and does not grow on glucose at 37°C but grows on both ethanol and glucose at 27°C. In this strain rho - petites are non-viable.

Communicated by F. Kaudewitz