Psychopharmacologia

, Volume 20, Issue 2, pp 169–171

Exploratory behavior in chronic disulfoton poisoning in mice

Authors

  • George Clark
    • Department of AnatomyMedical University of South Carolina
    • Veterans Administration Hospital
    • Department of Human Ecology, School of HealthUniversity of Oklahoma
    • Rohrer, Hibler and Replogle
  • Anna G. Koester
    • Department of AnatomyMedical University of South Carolina
    • Veterans Administration Hospital
    • Department of Human Ecology, School of HealthUniversity of Oklahoma
    • Rohrer, Hibler and Replogle
  • David W. Pearson
    • Department of AnatomyMedical University of South Carolina
    • Veterans Administration Hospital
    • Department of Human Ecology, School of HealthUniversity of Oklahoma
    • Rohrer, Hibler and Replogle
Animal Studies

DOI: 10.1007/BF00404370

Cite this article as:
Clark, G., Koester, A.G. & Pearson, D.W. Psychopharmacologia (1971) 20: 169. doi:10.1007/BF00404370

Abstract

The behavior of four groups of white mice was compared using the “hole-board” test. One male and one female group were chronically poisoned with disulfoton while similar untreated male and female groups served as controls. The scores of the poisoned animals were significantly higher than those of the controls, indicating that the poisoned animals exhibited increased exploratory behavior. There were no sex differences.

Key-Words

Exploratory BehaviorDisulfotonAcetylcholinesteraseSex
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Copyright information

© Springer-Verlag 1971