, Volume 20, Issue 2, pp 169-171

Exploratory behavior in chronic disulfoton poisoning in mice

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The behavior of four groups of white mice was compared using the “hole-board” test. One male and one female group were chronically poisoned with disulfoton while similar untreated male and female groups served as controls. The scores of the poisoned animals were significantly higher than those of the controls, indicating that the poisoned animals exhibited increased exploratory behavior. There were no sex differences.

The experimental portion of this report was performed at the Civil Aeromedical Institute, FAA DOT, Oklahoma City, Oklahoma.
The disulfoton (Di-Syston) used in this study was supplied by the Chemagro Corporation, Kansas City, Kansas.