Antonie van Leeuwenhoek

, Volume 70, Issue 2, pp 223–242

Metabolic engineering of sugar catabolism in lactic acid bacteria

Authors

  • Willem M. de Vos
    • Department of Biophysical ChemistryNIZO
    • Department of MicrobiologyWageningen Agricultural University
Metabolism

DOI: 10.1007/BF00395934

Cite this article as:
de Vos, W.M. Antonie van Leeuwenhoek (1996) 70: 223. doi:10.1007/BF00395934

Abstract

Lactic acid bacteria are characterized by a relatively simple sugar fermentation pathway that, by definition, results in the formation of lactic acid. The extensive knowledge of traditional pathways and the accumulating genetic information on these and novel ones, allows for the rerouting of metabolic processes in lactic acid bacteria by physiological approaches, genetic methods, or a combination of these two. This review will discuss past and present examples and future possibilities of metabolic engineering of lactic acid bacteria for the production of important compounds, including lactic and other acids, flavor compounds, and exopolysaccharides.

Key words

Lactococcus lactisStreptococcus thermophilusmetabolismoxygenlactosepyruvatediacetylpolysaccharides
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Copyright information

© Kluwer Academic Publishers 1996