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Enhanced endurance in trained cyclists during moderate intensity exercise following 2 weeks adaptation to a high fat diet

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Abstract

These studies investigated the effects of 2 weeks of either a high-fat (HIGH-FAT: 70% fat, 7% CHO) or a high-carbohydrate (HIGH-CHO: 74% CHO, 12% fat) diet on exercise performance in trained cyclists (n = 5) during consecutive periods of cycle exercise including a Wingate test of muscle power, cycle exercise to exhaustion at 85% of peak power output [90% maximal oxygen uptake (\(\dot V\)O2max), high-intensity exercise (HIE)] and 50% of peak power output [60% \(\dot V\)O2max, moderate intensity exercise (MIE)]. Exercise time to exhaustion during HIE was not significantly different between trials: nor were the rates of muscle glycogen utilization during HIE different between trials, although starting muscle glycogen content was lower [68.1 (SEM 3.9) vs 120.6 (SEM 3.8) mmol · kg −1 wet mass, P < 0.01] after the HIGH-FAT diet. Despite a lower muscle glycogen content at the onset of MIE [32 (SEM 7) vs 73 (SEM 6) mmol · kg −1 wet mass, HIGH-FAT vs HIGH-CHO, P < 0.01], exercise time to exhaustion during subsequent MIE was significantly longer after the HIGH-FAT diet [79.7 (SEM 7.6) vs 42.5 (SEM 6.8) min, HIGH-FAT vs HIGH-CHO, P<0.01]. Enhanced endurance during MIE after the HIGH-FAT diet was associated with a lower respiratory exchange ratio [0.87 (SEM 0.03) vs 0.92 (SEM 0.02), P<0.05], and a decreased rate of carbohydrate oxidation [1.41 (SEM 0.70) vs 2.23 (SEM 0.40) g CHO · min−1, P<0.05]. These results would suggest that 2 weeks of adaptation to a high-fat diet would result in an enhanced resistance to fatigue and a significant sparing of endogenous carbohydrate during low to moderate intensity exercise in a relatively glycogen-depleted state and unimpaired performance during high intensity exercise.

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References

  • Ayalon A, Inbar O, Bar-Or O (1974) Relationships among measurements of explosive strength and anaerobic power. In: Nelson RC, Morehouse CA (eds) Biomechanic IV. International Series on Sport Sciences, vol 1. University Press, Baltimore, pp 572–577

    Google Scholar 

  • Beck-Nielsen H, Pederson O, Sorensen NS (1978) Effects of diet on the cellular insulin binding and the insulin sensitivity in young healthy subjects. Diabetologia 15:289–296

    Google Scholar 

  • Bergstrom J (1962) Muscle electrolytes in man. Scand J Clin Lab Med 14:S11-S13

    Google Scholar 

  • Bergstrom J, Hermansen L, Hultman E, Saltin B (1967) Diet, muscle glycogen and physical performance. Acta Physiol Scand 71:140–150

    Google Scholar 

  • Bosch AN, Dennis SC, Noakes TD (1993) Influence of carbohydrate-loading on fuel substrate turnover and oxidation during prolonged exercise. J Appl Physiol 74:1921–1927

    Google Scholar 

  • Bosch AN, Dennis SC, Noakes TD (1994) Influence of carbohydrate ingestion on fuel substrate turnover and oxidation during prolonged exercise. J Appl Physiol 76:2364–2372

    Google Scholar 

  • Christensen EH, Hansen O (1939) Zur Methodik der respiratorischen Quotient-Bestimmung in Ruhe und bei Arbeit. III. Arbeitsfahigkeit und Ernährung. Skand Arch Physiol 81:160–171

    Google Scholar 

  • Coetzer P, Noakes TD, Sanders B, Lambert MI, Bosch AB, Wiggins T, Dennis SC (1993) Superior fatigue resistance of elite black South African distance runners. J Appl Physiol 75:1822–1827

    Google Scholar 

  • Coggan AR, Coyle EF (1987) Reversal of fatigue during prolonged exercise by carbohydrate infusion and ingestion. J Appl Physiol 63:2388–2395

    Google Scholar 

  • Coggan AR, Coyle EF (1991) Carbohydrate ingestion during prolonged exercise: effects on metabolism and performance. In: Holloszy JO (ed) Exercise Sports Science Review, vol 19. Williams and Wilkins, Baltimore, pp 1–40

    Google Scholar 

  • Coulee RK, Hammer RL, Winder WW, Bracken ML, Nelson AG, Barnett DW (1990) Glycogen repletion and exercise endurance in rats adapted to a high fat diet. Metabolism 39:289–294

    Google Scholar 

  • Consolazio CR, Johnson RE, Pecora LT (1963) Physiological measurements of metabolic functions in man. McGraw-Hill, New York

    Google Scholar 

  • Costill DL; Coyle EF, Dalsky G, Evans W, Fink W, Hoopes D (1977) Effects of elevated plasma FFA and insulin on muscle glycogen usage during exercise. J Appl Physiol 43:695–699

    Google Scholar 

  • Coyle EF, Coggan AR, Hemmert MK, Ivy JL (1986) Muscle glycogen utilization during prolonged strenuous exercise when fed carbohydrate. J Appl Physiol 61:163–172

    Google Scholar 

  • Durnin JVGA, Womersley J (1974) Body fat assessed from the total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16–72 years. Br J Nutr 32:77–97

    Google Scholar 

  • Eggstein M, Kuhlmann E (1974) Triglycerides and glycerol. Determination after alkaline hydrolysis. In: Bergmeyer HU (ed) Methods of enzymatic analysis. Academic Press, New York, pp 1825–1831

    Google Scholar 

  • Erp-Baart AMJ van, Saris WHM, Binkhorst RA, Vos JA, Elvers JHW (1989) Nationwide survey on nutritional habits in elite athletes, I. Energy, carbohydrate, protein, and fat intake. Int J Sports Med 10:S3-S10

    Google Scholar 

  • Evans WJ, Phinney SD, Young VR (1982) Suction applied to muscle biopsy maximizes sample size. Med Sci Sports Exerc 14:101–102

    Google Scholar 

  • Fisher EC, Evans WJ, Phinney SD, Blackburn GL, Bistrian BR, Young VR (1983) Changes in skeletal muscle metabolism induced by a eucaloric ketogenic diet. In: Knuttgen HG, Vogel JA, Poortsmans J (eds) Biochemistry of exercise: International Series on Sports Sciences, vol 13. Human Kinetics, Champaign, Ill., pp 497–501

    Google Scholar 

  • Galbo H, Holst JJ, Christensen NJ (1979) The effect of different diets and of insulin on the hormonal response to prolonged exercise. Acta Physiol Scand 107:19–32

    Google Scholar 

  • Gutman I, Wahlefeld AW (1974) L-(+)-Lactate determination with lactate dehydrogenase and NAD. In: Bergmeyer HU (ed) Methods of enzymatic analysis. Academic Press, New York, pp 1464–1486

    Google Scholar 

  • Hammel EP, Kronfeld DS, Ganjam VK, Dunlap HL (1977) Metabolic responses to exhaustive exercise in racing sled dogs fed diets containing medium, low, or zero carbohydrate. Am J Clin Nutr 30:409–418

    Google Scholar 

  • Hargreaves M, Kiens B, Richter EA (1991) Effect of increased plasma free fatty acid concentrations on muscle metabolism in exercising men. J Appl Physiol 70:194–201

    Google Scholar 

  • Hawley JA, Noakes TD (1992) Peak power output predicts maximal oxygen uptake and performance time in trained cyclists. Eur J Appl Physiol 65:79–83

    Google Scholar 

  • Hawley JA, Bosch AN, Weltan SM, Dennis SC, Noakes TD (1994) The effects of glucose ingestion or glucose infusion on fuel substrate kinetics during prolonged exercise. Eur J Appl Physiol 68:381–389

    Google Scholar 

  • Jenkins AB, Storlien LH, Chisholm DJ, Kraegen EW (1988) Effects of nonesterified fatty acid availability on tissue-specific glucose utilization in rats in vivo. J Clin Invest 82:293–299

    Google Scholar 

  • Kronfeld DS, Hammel EP, Ramberg CF, Dunlap HL (1973) Hematological and metabolic responses to training in racing sled dogs fed diets containing medium, low, or zero carbohydrate. Am J Clin Nutr 30:419–430

    Google Scholar 

  • Kuipers H, Verstappen FTJ, Keizer HA, Guerten P, Van Kraneburg G (1985) Variability of aerobic performance in the laboratory and its physiological correlates. Int J Sports Med 6:197–201

    Google Scholar 

  • Maughan RJ, Poole DC (1981) The effects of a glycogen loading regime on the capacity to perform anaerobic exercise. Eur J Appl Physiol 46:211–219

    Google Scholar 

  • Miller WC, Bryce GR, Coulee RK (1984) Adaptations to a high-fat diet that increase exercise endurance in male rats. J Appl Physiol 56:78–83

    Google Scholar 

  • Nadeau M, Brassard A (1983) The bicycle ergometer for muscle power testing. Can J Appl Sport Sci 8:41–46

    Google Scholar 

  • Passoneau JV, Lauderdale VR (1974) A comparison of three methods of glycogen measurement in tissues. Anal Biochem 60:405–417

    Google Scholar 

  • Phinney SD, Bistrian BR, Evans WF, Gervino E, Blackburn GL (1983) The human metabolic response to chronic ketosis without caloric restriction: preservation of submaximal exercise capability with reduced carbohydrate oxidation. Metabolism 32:769–776

    Google Scholar 

  • Pruett EDR (1970) Glucose and insulin during prolonged work stress in men living on different diets. J Appl Physiol 28:199–208

    Google Scholar 

  • Rennie MJ, Winder WW, Holloszy JO (1976) A sparing effect of increasing plasma fatty acids on muscle and liver glycogen content in the exercising rat. Biochem J 156:647–655

    Google Scholar 

  • Saltin B, Karlsson J (1971) Muscle glycogen utilization during work of different intensities. Adv Exp Med Biol 11:289–299

    Google Scholar 

  • Schutz Y, Ravussin E (1980) Respiratory quotients lower than 0.70 in ketogenic diets. Am J Clin Nutr 33:1317–1318

    Google Scholar 

  • Simi B, Sempore B, Mayet MH, Favier RJ (1991) Additive effects of training and high-fat diet on energy metabolism during exercise. J Appl Physiol 71:197–203

    Google Scholar 

  • Weiland O (1974) Glycerol, UV-method. In: Bergmeyer HU (ed) Methods of enzymatic analysis. Academic Press, New York, pp 1404–1409

    Google Scholar 

  • Williamson DH, Mellanby J (1974) D-(−)-3-Hydroxybutyrate. In: Bergmeyer HU (ed) Methods of enzymatic analysis. Academic Press, New York, pp 1836–1837

    Google Scholar 

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Lambert, E.V., Speechly, D.P., Dennis, S.C. et al. Enhanced endurance in trained cyclists during moderate intensity exercise following 2 weeks adaptation to a high fat diet. Eur J Appl Physiol 69, 287–293 (1994). https://doi.org/10.1007/BF00392032

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