Human Genetics

, Volume 79, Issue 3, pp 283–285

Regional chromosomal localisation of APOA2 to 1q21–1q23

  • H. R. Middleton-Price
  • J. A. van den Berghe
  • J. Scott
  • T. J. Knott
  • S. Malcolm
Original Investigations

DOI: 10.1007/BF00366253

Cite this article as:
Middleton-Price, H.R., van den Berghe, J.A., Scott, J. et al. Hum Genet (1988) 79: 283. doi:10.1007/BF00366253

Summary

Using in situ hybridisation, we have mapped APOA2 to the 1q21–1q23 region of chromosome 1. DNA hybridisation to somatic cell hybrids made from cells carrying a balanced translocation between X and 1 confirms the localisation as proximal to 1q23. This was further confirmed by the presence of two polymorphic alleles in a cell line carrying a deletion of 1q25–1q32.

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • H. R. Middleton-Price
    • 1
  • J. A. van den Berghe
    • 1
  • J. Scott
    • 2
  • T. J. Knott
    • 2
  • S. Malcolm
    • 1
  1. 1.Mothercare Department of Paediatric GeneticsInstitute of Child HealthLondonUK
  2. 2.Climical Research CentreHarrowUK

Personalised recommendations