Short Communications

Current Genetics

, Volume 13, Issue 5, pp 445-449

First online:

Discrimination between different groups of Candida parapsilosis by mitochondrial DNA restriction analysis

  • Nadine CamougrandAffiliated withInstitut de Biochimie Cellulaire et Neurochimie du CNRS
  • , Bernard MilaAffiliated withInstitut de Biochimie Cellulaire et Neurochimie du CNRS
  • , Gisèle VeloursAffiliated withInstitut de Biochimie Cellulaire et Neurochimie du CNRS
  • , Jaga LazowskaAffiliated withCentre de Génétique Moleculaire du CNRS
  • , Martine GuèrinAffiliated withInstitut de Biochimie Cellulaire et Neurochimie du CNRS

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Summary

The analysis of mitochondria' DNA (mtDNA) from several strains of Candida parapsilosis and Candida rhagii by restriction endonucleases enabled us to discriminate between several groups within the C. parapsilosis species and to allocate laboratory strains to one of these. The mtDNAs isolated ranged in size from 20 to 31 kb. The mtDNA isolated from group 1 C. parapsilosis hybridises with both ATPase subunit 6 and 8 gene probes, the same restriction fragment hybridising with both probes.

Key words

C. parapsilosis C. rhagii Mitochondrial DNA