Original Contributions

Mammalian Genome

, Volume 3, Issue 1, pp 36-38

First online:

Two members of the JAK family of protein tyrosine kinases map to Chromosomes 1p31.3 and 9p24

  • Melanie A. PritchardAffiliated withDepartment of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital
  • , Elizabeth BakerAffiliated withDepartment of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital
  • , David F. CallenAffiliated withDepartment of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital
  • , Grant R. SutherlandAffiliated withDepartment of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital
  • , Andrew F. WilksAffiliated withLudwig Institute for Cancer Research

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Abstract

A member of a new class of protein tyrosine kinases, JAK1, has been mapped to 1p31.3 by in situ hybridization and Southern blot analysis of a panel of mouse-human hybrid cell lines. A murine protein tyrosine kinase, related to, but distinct, from JAK1, was mapped by in situ hybridization to human Chromosome (Chr) 9p24 and 1p31.3.