Molecular and General Genetics MGG

, Volume 216, Issue 2, pp 183–187

Multiple genes are transcribed in Hordeum vulgare and Zea mays that carry the DNA binding domain of the myb oncoproteins

  • Adriano Marocco
  • Margit Wissenbach
  • Dieter Becker
  • Javier Paz-Ares
  • Heinz Saedler
  • Francesco Salamini
  • Wolfgang Rohde
Article

DOI: 10.1007/BF00334354

Cite this article as:
Marocco, A., Wissenbach, M., Becker, D. et al. Mol Gen Genet (1989) 216: 183. doi:10.1007/BF00334354

Summary

cDNA clones were isolated from tissue specific cDNA libraries of barley and maize using as a probe the cDNA of the maize gene C1, a regulator of anthocyanin gene expression. C1-related homology for all of the four cDNAs characterized by sequence analysis is restricted to the N-terminal 120 amino acids of the putative proteins. This region shows striking homology to the N-proximal domain of the myb oncoproteins from vertebrates and invertebrates. Within the myb proto-oncogene family this part of the respective gene products functions as a DNA binding domain. Acidic domains are present in the C-proximal protein segments. Conservation of these sequences, together with the genetically defined regulator function of the C1 gene product, suggest that myb-related plant genes code for trans-acting factors which regulate gene expression in a given biosynthetic pathway.

Key words

Plant genesmyb proto-oncogene homoloy

Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • Adriano Marocco
    • 1
  • Margit Wissenbach
    • 1
  • Dieter Becker
    • 1
  • Javier Paz-Ares
    • 1
  • Heinz Saedler
    • 1
  • Francesco Salamini
    • 1
  • Wolfgang Rohde
    • 1
  1. 1.Max-Planck-Institut für ZüchtungsforschungKöln 30Federal Republic of Germany