, Volume 198, Issue 1, pp 175-176

Competition between isogenic mutS and mut + populations of Escherichia coli K12 in continuously growing cultures

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Previous studies have shown that the mutT, mutH and mutL mutators of Escherichia coli have a marked advantage in competition growth with otherwise coisogenic wild-type strains. As shown in this paper the same is true for the mutS mismatch mutator. In three experiments mutS could outgrow the wild-type and had higher fitness values.

Communicated by H. Böhme