World Journal of Urology

, Volume 6, Issue 3, pp 175–178

Incidence, pathophysiology and treatment of prolonged erections

  • C. G. Stief
  • W. Bähren
  • H. Gall
  • W. Scherb
Free Paper

DOI: 10.1007/BF00326797

Cite this article as:
Stief, C.G., Bähren, W., Gall, H. et al. World J Urol (1988) 6: 175. doi:10.1007/BF00326797


Prolonged erections (pharmacologically induced erections over 6 hours) are the most inconvenient side effects encountered in the diagnosis and therapy of erectile dysfunction with intracavernous injection of vasoactive drugs. Out of a total of 29 prolonged erections, 26 were seen after diagnostic use in 300 patients and 3 after therapeutic application in more than 4800 protocolled autoinjection of a standardized vasoactive solution (papaverine hydrochloride 15 mg/ml and phentolamine mesylate 0.5 mg/ml). In 25 of these 29 prolonged erections intracavernous injections of the alpha-receptor stimulant metaraminol was done and led to flaccidity in all cases. Another patient with a papaverine-induced erection lasting 26 h did not respond to intracavernous metaraminol and required puncture and aspiration; he lost spontaneous erectability and cavernosal response to vasoactive drugs. Metaraminol was also injected intracavernosally in a further 32 patients with pharmacologically induced full erections: flaccidity was obtained in all patients.

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • C. G. Stief
    • 1
  • W. Bähren
    • 2
  • H. Gall
    • 3
  • W. Scherb
    • 4
  1. 1.Department of UrologyBWK, Academic Hospital of the University of UlmFRG
  2. 2.Department of RadiologyBWK, Academic Hospital of the University of UlmFRG
  3. 3.Department of DermatologyBWK, Academic Hospital of the University of UlmFRG
  4. 4.Department of Neurology and PsychiatryBWK, Academic Hospital of the University of UlmFRG