Anatomy and Embryology

, Volume 167, Issue 3, pp 321–333

Serotonergic innervation on the motoneurons in the mammalian brainstem

Light and electron microscopic immunohistochemistry
  • Y. Takeuchi
  • M. Kojima
  • T. Matsuura
  • Y. Sano
Article

DOI: 10.1007/BF00315670

Cite this article as:
Takeuchi, Y., Kojima, M., Matsuura, T. et al. Anat Embryol (1983) 167: 321. doi:10.1007/BF00315670

Summary

A comparative study of serotonergic innervation on motoneurons in the brainstem of various mammals (mouse, rat, guinea pig, dog, cat and monkey) was carried out using a sensitive immunohistochemical method. Except for the extraocular muscle nuclei, the motor nuclei of the cranial nerves received rich inputs from serotonin neurons, in all species examined — rodent, carnivore and primate. The motoneurons of the monkey were innervated by varicose serotonin fibers, in a manner different from that of other species, i.e. their cell bodies and proximal dendrites were tightly encircled by a large number of serotonin-containing varicose fibers. At the ultrastructural level, a predominant population of axosomatic contacts was confirmed in the cranial motor nuclei of the monkey, particularly in the nucleus ambiguus.

Key words

SerotoninImmunohistochemistryBrainstemMotoneuronMonkey

Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • Y. Takeuchi
    • 1
  • M. Kojima
    • 1
  • T. Matsuura
    • 1
  • Y. Sano
    • 1
  1. 1.Department of AnatomyKyoto Prefectural University of MedicineKyotoJapan