Acta Neuropathologica

, Volume 90, Issue 4, pp 415–418

Senile plaques in an aged two-humped (Bactrian) camel (Camelus bactrianus)

  • Shin-ichiro Nakamura
  • Hiroyuki Nakayama
  • Koji Uetsuka
  • Nobuo Sasaki
  • Kazuyuki Uchida
  • Naoaki Goto
Case Report

DOI: 10.1007/BF00315016

Cite this article as:
Nakamura, S., Nakayama, H., Uetsuka, K. et al. Acta Neuropathol (1995) 90: 415. doi:10.1007/BF00315016
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Abstract

Senile plaques with β-protein as a major constituent are a conspicuous feature in the brains of aged humans, monkeys, dogs, and bears. We found cerebral senile plaques of the diffuse and primitive type, but not the classical type, in an aged female camel of more than 20 years old. The senile plaques and a few cortical capillaries were immunoreactive with anti-β-protein serum. Congophilic amyloid deposition was detected in a small number of the capillaries, but not in the senile plaques. We believe this to be the first detailed report of senile plaques in a herbivore, and these findings suggest the ossibility of senile plaque formation in a wide variety of mammlian species.

Key words

Camel Senile plaque β-protein 

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • Shin-ichiro Nakamura
    • 1
  • Hiroyuki Nakayama
    • 1
  • Koji Uetsuka
    • 1
  • Nobuo Sasaki
    • 3
  • Kazuyuki Uchida
    • 2
  • Naoaki Goto
    • 1
  1. 1.Department of Veterinary Pathology, Faculty of AgricultureThe University of TokyoTokyoJapan
  2. 2.Department of Veterinary Pathology, Faculty of AgricultureMiyazaki UniversityMiyazakiJapan
  3. 3.Department of Veterinary Surgery, Faculty of AgricultureThe University of TokyoTokyoJapan

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