Senile plaques in an aged two-humped (Bactrian) camel (Camelus bactrianus)
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- Nakamura, S., Nakayama, H., Uetsuka, K. et al. Acta Neuropathol (1995) 90: 415. doi:10.1007/BF00315016
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Senile plaques with β-protein as a major constituent are a conspicuous feature in the brains of aged humans, monkeys, dogs, and bears. We found cerebral senile plaques of the diffuse and primitive type, but not the classical type, in an aged female camel of more than 20 years old. The senile plaques and a few cortical capillaries were immunoreactive with anti-β-protein serum. Congophilic amyloid deposition was detected in a small number of the capillaries, but not in the senile plaques. We believe this to be the first detailed report of senile plaques in a herbivore, and these findings suggest the ossibility of senile plaque formation in a wide variety of mammlian species.