, Volume 16, Issue 3, pp 206–219

Histochemical aspects of the differentiation of adventitious cartilage on the membrane bones of the embryo chick

  • B. K. Hall

DOI: 10.1007/BF00307849

Cite this article as:
Hall, B.K. Histochemie (1968) 16: 206. doi:10.1007/BF00307849


The histochemistry of the adventitious cartilage of the chick has been studied and compared with both primary cartilage and the bone on which the adventitious cartilage develops. The distribution of DNA, RNA, collagen, acid mucopolysaccharide, mucoprotein, glycogen, lipid, alkaline phosphatase and inorganic phosphate has been studied. Adventitious cartilage was found to have the histochemistry of primary hypertrophic cartilage and to calcify. The appearance of lipid and alkaline phosphatase activity coincided with the onset of calcification.

The proliferating osteogenic and chondrogenic cells of the chick embryo have been classified and compared histochemically. Collagen synthesis was found to be high in the osteogenic cells and acid mucopolysaccharide and mucoprotein synthesis high in the chondrogenic cells.

It has been postulated that the morphogenetic switch from osteogenesis to adventitious chondrogenesis most probably involves a change in the rate of collagen and acid mucopolysaccharide synthesis by the germinal cells of the membrane bones.

Copyright information

© Springer-Verlag 1968

Authors and Affiliations

  • B. K. Hall
    • 1
    • 2
  1. 1.Department of ZoologyUniversity of New EnglandArmidaleAustralia
  2. 2.Department of BiologyDalhousie UniversityHalifaxCanada