, Volume 9, Issue 7, pp 380-386

Lissencephaly syndromes: clinical aspects

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We report clinical and neurophysiological findings in six children (three female, three male) with type I lissencephaly and three children (all female) with type II lissencephaly (Walker-Warburg syndrome). In type I lissencephaly the diagnosis is based only on electroencephalographic (EEG) signs, whereas in type II lissencephaly the diagnosis rests on clinical signs. In type I lissencephaly the EEG typically shows high α-β activity, which is not seen in type II lissencephaly.

Presented at the Symposium on Lissencephaly and Related Disorders, Münster, Germany, 13 July 1992