A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients
- Cite this article as:
- Black, W.C. & Krafsur, E.S. Theoret. Appl. Genetics (1985) 70: 491. doi:10.1007/BF00305981
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A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domestica L.) are included to illustrate features of the program.