Anatomy and Embryology

, Volume 161, Issue 1, pp 115–120

Development of Dickie's small eye: An early lethal mutation in the house mouse


  • Karl Theiler
    • Anatomisches Institut der Universität Gloriastr. 19
  • Don S. Varnum
    • The Jackson Laboratory
  • Leroy C. Stevens
    • The Jackson Laboratory

DOI: 10.1007/BF00304672

Cite this article as:
Theiler, K., Varnum, D.S. & Stevens, L.C. Anat Embryol (1980) 161: 115. doi:10.1007/BF00304672


Mice heterozygous for Dickie's small eye (Dey) are small and have malformed eyes (Theiler et al. 1978). The development of homozygous Dey/Dey was more difficult to analyze than heterozygous Dey/+. This investigation attempted to identify the homozygotes and to distinguish them from Dey/+ and +/+ resorptions. Such a distinction was possible only when enough specimens were available. The mutants are poor breeders and the collection of the necessary material has taken several years.

Key words

Dickie's small eyeDevelopmentFetogenesisMouse

Copyright information

© Springer-Verlag 1980