, Volume 161, Issue 1, pp 115-120

Development of Dickie's small eye: An early lethal mutation in the house mouse

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Summary

Mice heterozygous for Dickie's small eye (Dey) are small and have malformed eyes (Theiler et al. 1978). The development of homozygous Dey/Dey was more difficult to analyze than heterozygous Dey/+. This investigation attempted to identify the homozygotes and to distinguish them from Dey/+ and +/+ resorptions. Such a distinction was possible only when enough specimens were available. The mutants are poor breeders and the collection of the necessary material has taken several years.

This work was supported by Research Grant CA 02662 from the National Cancer Institute
The Jackson Laboratory is fully accredited by the American Association for Accreditation of Laboratory Animal Care