Calcified Tissue International

, Volume 57, Issue 2, pp 97–99

Bone mineral density in patients with prostatic cancer treated with orchidectomy and with estrogens

  • S. Eriksson
  • A. Eriksson
  • R. Stege
  • K. Carlström
Clinical Investigations

DOI: 10.1007/BF00298427

Cite this article as:
Eriksson, S., Eriksson, A., Stege, R. et al. Calcif Tissue Int (1995) 57: 97. doi:10.1007/BF00298427

Abstract

Bone mineral density (BMD) and bone mineral content (BMC) were measured in the femoral neck area, trochanteric area and Wards triangle, and in the distal radius of the left forearm before and after 1 year of endocrine treatment in 27 patients with prostatic cancer. Eleven of the patients were treated with orchidectomy and 16 with combined oral and intramuscular estrogens. The patients were free from metastases during the entire observation period. In the orchidectomized patients, BMD and BMC of the distal radius decreased significantly following treatment, whereas no changes were observed in the estrogen-treated patients. These preliminary results demonstrate that estrogens may protect bone in male subjects also and may merit further investigations on larger groups of patients.

Key words

Bone mineral densityBone mineral contentProstatic cancerEndocrine treatment

Copyright information

© Springer-Verlag New York Inc 1995

Authors and Affiliations

  • S. Eriksson
    • 1
  • A. Eriksson
    • 2
  • R. Stege
    • 2
  • K. Carlström
    • 3
  1. 1.Department of Orthopedics, Karolinska InstitutetHuddinge University HospitalHuddingeSweden
  2. 2.Department of Urology, Karolinska InstitutetHuddinge University HospitalHuddingeSweden
  3. 3.Department of Obstetrics and Gynecology, Karolinska InstitutetHuddinge University HospitalHuddingeSweden