Calcified Tissue International

, Volume 50, Issue 5, pp 400–403

Calcitonin treatment in lumbar spinal stenosis: A randomized, placebo-controlled, double-blind, cross-over study with one-year follow-up

  • Antti Eskola
  • Timo Pohjolainen
  • Hannu Alaranta
  • Juhani Soini
  • Kaj Tallroth
  • Pär Slätis
Clinical Investigations

DOI: 10.1007/BF00296769

Cite this article as:
Eskola, A., Pohjolainen, T., Alaranta, H. et al. Calcif Tissue Int (1992) 50: 400. doi:10.1007/BF00296769

Summary

A randomized, placebo-controlled, double-blind, crossover study in 40 lumbar spinal stenosis patients with a 1-year follow-up showed that calcitonin had beneficial effects on the patients' symptoms without producing any notable side effects. Calcitonin had a clear analgesic effect. The mean of walking distance increased, but the crossover trend was not as good as the analgesic effect. Side effects such as erythema and nausea were usually mild and transient. Calcitonin therapy can be used as a conservative treatment in selected cases of lumbar spinal stenosis. When rest pain was mild or the walking distance was under 200–300 m because of neurogenic claudication, the effect of calcitonin seemed to be poor.

Key words

Calcitonin therapy Lumbar spinal stenosis 

Copyright information

© Springer-Verlag New York Inc 1992

Authors and Affiliations

  • Antti Eskola
    • 1
  • Timo Pohjolainen
    • 1
  • Hannu Alaranta
    • 1
  • Juhani Soini
    • 1
  • Kaj Tallroth
    • 1
  • Pär Slätis
    • 1
  1. 1.The Orthopaedic Hospital of the Invalid FoundationHelsinkiFinland
  2. 2.HelsinkiFinland

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